|
KMID : 0545120010110020346
|
|
Journal of Microbiology and Biotechnology
2001 Volume.11 No. 2 p.346 ~ p.349
|
|
|
Antimutagenic Effect of Polysaccharides Extracted from Soybeans Fermented with Basidiomycetes on 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline(MeIQx)
|
|
SHON, YUN-HEE
KIM, SO-YEUN/LEE, JAE-SUNG/LIM, JONG-KOOK/NAM, KYUNG-SOO
|
|
|
Abstract
|
|
|
|
The antimutagenic activity of polysaccharides extracted from soybeans fermented with Agrocybe cylindracea (AC) or Phellinus igniarius (PI) against 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) was examined using a Salmonella/Ames test and host-mediated assay in mice. The polysaccharides from the soybeans fermented with A. cylindracea and P. igniarius inhibited the mutagenic activity of the cooked food mutagen, MeIQx, by 31.2% and 35.3%, respectively. The polysaccharides also inhibited MeIQx genotoxicity in a dose-dependent manner in mice. These results suggest that the polysaccharides from soybeans fermented with A. cylindracea or P. igniarius exhibit antimutagenic properties against MeIQx in vitro and in vivo.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|